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大手筋 (おおてすじ) — large-scale operators; big traders
大手筋
large-scale operators
筋 「すじ」「きん」
muscle; tendon; sinew
筋者 「すじもの」「すじもん」
yakuza
三筋 みすじ
misuji (cut of beef, usu. from the chuck)
大手術 だいしゅじゅつ
major surgery; major operation
大の苦手 だいのにがて
being extremely bad or uncomfortable (at or with something); having a dread (of something)